caudal additives do not improve the analgesia afforded by levobupivacaine after hypospadias repair
نویسندگان
چکیده
conclusions the addition of s (+)-ketamine or clonidine to levobupivacaine 0.25% in caudal analgesia for hypospadias repair appears to be of no benefit. however, use of the additives in combination increased postoperative sedation. results the 87 patients included had a mean ± sd age of 21.4 ± 13.5 months and weight of 11.9 ± 2.4 kg. the median doses of levobupivacaine, s (+)-ketamine, and clonidine were 0.7 mg/kg (range, 0.4–1.3), 0.5 mg/kg (0.2–1.1), and 1.8 μg/kg (0.8–2.3), respectively. the addition of s(+)-ketamine, clonidine, or both did not increase the time to first oral analgesia request. neither did it reduce the total first 24-hour postoperative analgesia requirements or alter hospital discharge time. however, the additive drugs in combination did increase postoperative sedation. patients and methods we conducted a retrospective chart analysis for all patients who underwent hypospadias repair with caudal analgesia over a consecutive 3-period at this institution. the study examined four patient groups, classified according to the analgesia used:rn1) no additive, levobupivacaine alonern2) levobupivacaine and s (+)-ketaminern3) levobupivacaine and clonidinern4) levobupivacaine, s (+)-ketamine, and clonidinernprimary outcome measures were as follows: time to the first postoperative request for analgesia, total first 24-hour postoperative analgesia, and time to hospital discharge.rn background caudal analgesia is commonly employed to provide excellent intra- and postoperative analgesia for primary hypospadias repair in children. several additives to local anesthetics are commonly employed to increase the block duration, although these have uncertain benefits. objectives this study investigated whether, in caudal analgesia with levobupivacaine 0.25%, the addition of s (+)-ketamine, clonidine, or both agents combined, would prolong postoperative analgesia in patients undergoing primary hypospadias repair.
منابع مشابه
Caudal Additives Do Not Improve the Analgesia Afforded by Levobupivacaine After Hypospadias Repair
BACKGROUND Caudal analgesia is commonly employed to provide excellent intra- and postoperative analgesia for primary hypospadias repair in children. Several additives to local anesthetics are commonly employed to increase the block duration, although these have uncertain benefits. OBJECTIVES This study investigated whether, in caudal analgesia with levobupivacaine 0.25%, the addition of S (+)...
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Ninety boys, aged 13-53 months, undergoing repair of hypospadias, were allocated randomly to receive 0.8 ml kg-1 of one of three solutions into the caudal extradural space: group B received bupivacaine 2 mg kg-1, group T received tramadol 2 mg kg-1 in 0.9% saline and group BT a mixture of both. Postoperative pain was assessed hourly for 12 h after injection using a modified TPPPS pain score and...
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متن کاملComparison of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery.
OBJECTIVE To compare the effectiveness of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery. STUDY DESIGN Quasi experimental study. PLACE AND DURATION OF STUDY The Postgraduate Medical Institute, Hayatabad Medical Complex, Peshawar, from February 2006 to August 2007. METHODOLOGY The study was conducted on 60 male children un...
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عنوان ژورنال:
anesthesiology and pain medicineجلد ۱، شماره ۳، صفحات ۱۷۴-۱۷۷
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